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DNA Tests For Medicine Conflicts
Have you every done a DNA test to see what your genetic makeup is of your family, race, origin, etc? They are really cool. Many are full of surprises. People get excited to see how they connect with their family and other parts of the world. Well, besides a DNA test for genetic makeup there are also ones for medical history and interaction. This is so cool! I just recently heard about this test and was excited to try it. My son is on four different prescription medications and I thought it was a great idea to get a PanaceaPGX test kit to see what they say about how his DNA works with the medication he is taking.
Some results from his test:
- Moderate risk of Anti-psychotic-induced Tardive Dyskinesia.
- Moderate risk of Antipsychotic-induced Hyperprolactinemia.
- Moderate risk of Anti-psychotic-Induced Weight Gain.
- Negaive for Type III Hyperlipoproteinemia.
- No increased risk of Hyperhomocysteinemia. Meaning his folate and homocysteine markers are fine.
- No increased risk of Thrombophilia. Meaning he does not carry the Facor V Leiden G1691A mutation or Factor II G20210A mutation.
- No increased risk of Hyperhomocysteinemia.
All of this is a lot of big medical terms/verbiage so I was glad a doctor called me and explained each and every one and what it meant in regards to my son and the medication he takes and any medication he might need to take in the future.
What To Do?
The test kit was easy to understand, easy to use and we did it in just a few minutes. I had my son clean his mouth, wait about 15-20 minutes without eating or drinking anything and then I had long swabs to do a cheek swab. I put them back in the prepaid envelope, put it in the mail and I received the results in a few weeks. A doctor even called me to go over the results with me, asking me if I had any questions and explaining the comprehensive report. I can also sign a release to have the report sent to my son’s pediatrician and psychiatrist. I love that I was able to order the test kit online, have it arrive by mail, sent back by mail and receive the results by email.
Who Is Testing And Why?
The company doing the research is PanaceaPGX to promote their PGX testing. miGene™ is based on pharmacogenetics-the study of how genetic makeup affects a person’s response to medicine. As a leader in Personalized Medicine, PanaceaPGX offers a wide range of testing solutions to help both the patient and physician determine which is the right drug and the right dose for you. miGene™ is the cornerstone of personalized medicine. This testing and process is HIPAA compliant, and PanaceaPGX does not sell your information to pharmaceutical companies.
Results you are looking for: Determining how well you metabolize medication raises chances of a positive outcome and reduces possible adverse drug related reactions. miGene™ conveys a blueprint to how your body’s unique molecular characteristics and distinctions allow it to process medication. Your physician will have the data necessary to custom tailor the management of medications that are the best alternatives for you.
If one or more of the following criteria applies to your medical management, then you should consider pharmacogenetic testing:
- Uses two or more prescribed medications
- Has had adverse drug related reactions (ADR)
- Doesn’t feel their medication is working effectively
- Concerned about making a change in medication
- Candidate for Antiplatelet, Anticoagulant, Statin Rx
- ACS-PCI, Warfarin initiation, Simvastatin/ Atorvastatin Rx
- Unstable INR, bleeding, thrombotic event, muscle weakness
- Effient, Brilinta, Pradaxa, Xarelto Rx
- Has a history of heart attack or stent replacement
- Candidate for Opioid Rx
- Opioid ADR, sub-optimal response, high dose requirement
- Side effects to NSAIDs, muscle relaxers, triptans, considering switch to patch
- Abnormal opioid UDT Experiences chronic pain
- Candidate for Psychotropic Rx
- Dx Depression, Treatment Resistant Depression, psychosis Psychotropic ADR or sub optimal response
- More than 1 psychotropic Rx
- Treatment resistant, uncontrolled, hospital admission in past 6 months
- Is depressed or has treatment-resistant depression
Of course anyone can order this test. But the majority of people doing it are ones that want to see medicines that work best for them, or to check for conflicts in medicine or other types of medicine that might be more efficient. When I was on the phone the doctor talked about medicines that would work better, worse or not be effective for my son and his ADHD. It was crazy, because I told him, after, about two types of medications we had tried before settling on the one he is currently taking. One of them worked great but made my son lose too much weight. One didn’t work very well at all. The current one is good but not as good as the first. He had to stop taking the first one, due to the weight loss, so the third one is the one we found works the best without losing weight.
With different classes of medicine (anticancer agents, cardiovascular, diabetes, gastrointestinal, infection, pain, etc).
I have a list of the category, drug class and if each is in one of three categories:
- Standard Precautions.
- Use With Caution.
- Consider Alternatives.
Costs & How To Order
My readers can order the test for $499, instead of $799. You can use the following link to access the discounted order form: PanaceaPGX site.
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